Zhinan Yin Selected Research

tylophorine

2/2019	NK007 helps in mitigating paclitaxel resistance through p38MAPK activation and HK2 degradation in ovarian cancer.
9/2014	Synthesis of novel tylophorine derivatives and evaluation of their anti-inflammatory activity.
1/2013	A novel tylophorine analog W-8 up-regulates forkhead boxP3 expression and ameliorates murine colitis.
12/2012	A novel tylophorine analog NK-007 ameliorates colitis through inhibition of innate immune response.
9/2012	Therapeutic effects of a novel tylophorine analog, NK-007, on collagen-induced arthritis through suppressing tumor necrosis factor α production and Th17 cell differentiation.
3/2006	Effects of a novel tylophorine analog on collagen-induced arthritis through inhibition of the innate immune response.

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Zhinan Yin Research Topics

Disease

39	Neoplasms (Cancer) 10/2022 - 08/2003
13	Inflammation (Inflammations) 08/2019 - 03/2006
9	Infections 01/2022 - 08/2007
5	Systemic Lupus Erythematosus (Libman-Sacks Disease) 11/2014 - 01/2011
5	Arthritis (Polyarthritis) 09/2012 - 09/2004
4	Virus Diseases (Viral Diseases) 01/2019 - 09/2003
4	Carcinogenesis 12/2018 - 07/2007
4	Colitis 12/2018 - 12/2012
4	Breast Neoplasms (Breast Cancer) 02/2014 - 01/2010
4	Atherosclerosis 09/2013 - 02/2010
3	Fibrosis (Cirrhosis) 04/2022 - 08/2014
3	Hypersensitivity (Allergy) 01/2022 - 01/2017
3	Neoplasm Metastasis (Metastasis) 01/2022 - 10/2011
3	Experimental Melanoma 01/2021 - 07/2013
3	Communicable Diseases (Infectious Diseases) 05/2019 - 11/2010
3	Hepatitis 01/2017 - 11/2011
3	Lupus Nephritis 07/2013 - 01/2013
3	Melanoma (Melanoma, Malignant) 07/2013 - 08/2003
3	Experimental Arthritis 09/2012 - 03/2006
2	COVID-19 03/2022 - 01/2020
2	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 01/2018
2	Stomach Neoplasms (Stomach Cancer) 01/2022 - 12/2015
2	Obesity 12/2021 - 01/2020
2	Lung Neoplasms (Lung Cancer) 01/2021 - 01/2017
2	Pancreatic Neoplasms (Pancreatic Cancer) 10/2020 - 10/2018
2	Psoriasis (Pustulosis Palmaris et Plantaris) 10/2020 - 01/2020
2	Lymphatic Metastasis 01/2019 - 10/2011
2	Carcinoma (Carcinomatosis) 10/2018 - 10/2011
2	Wounds and Injuries (Trauma) 01/2018 - 01/2017
2	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2017 - 06/2014
2	Pulmonary Fibrosis (Fibrosing Alveolitis) 02/2015 - 07/2004
2	Autoimmune Diseases (Autoimmune Disease) 09/2014 - 07/2013
2	Asthma (Bronchial Asthma) 04/2014 - 11/2013
2	Fibrosarcoma 01/2014 - 07/2013
2	Anaplasmosis 01/2008 - 08/2007
1	Fever (Fevers) 10/2022
1	Liver Cirrhosis (Hepatic Cirrhosis) 04/2022
1	Hearing Loss (Hearing Impairment) 01/2022
1	Epistaxis (Nosebleed) 01/2022
1	Earache (Otalgia) 01/2022
1	Dyspnea (Shortness of Breath) 01/2022
1	Nausea 01/2022
1	Dizziness (Lightheadedness) 01/2022
1	Deafness (Deaf Mutism) 01/2022
1	Sepsis (Septicemia) 01/2022
1	Reinfection 01/2022

Drug/Important Bio-Agent (IBA)

12	CytokinesIBA 01/2020 - 08/2003
8	Interleukin-17 (Interleukin 17)IBA 01/2018 - 05/2010
6	Proteins (Proteins, Gene)FDA Link 10/2020 - 03/2010
6	tylophorineIBA 02/2019 - 03/2006
5	Biomarkers (Surrogate Marker)IBA 01/2020 - 10/2011
5	Pharmaceutical PreparationsIBA 01/2019 - 08/2012
4	Mechanistic Target of Rapamycin Complex 2IBA 04/2022 - 01/2018
4	AntigensIBA 01/2022 - 03/2007
4	Interleukin-27 (Interleukin 27)IBA 12/2021 - 07/2013
4	Transcription Factors (Transcription Factor)IBA 01/2019 - 08/2007
4	Phosphotransferases (Kinase)IBA 01/2018 - 07/2007
4	DNA (Deoxyribonucleic Acid)IBA 07/2013 - 01/2011
3	Interleukin-10 (Interleukin 10)IBA 01/2022 - 01/2011
3	PerforinIBA 01/2020 - 09/2003
3	Paclitaxel (Taxol)FDA LinkGeneric 02/2019 - 08/2012
3	Therapeutic UsesIBA 01/2018 - 09/2012
3	InterferonsIBA 01/2017 - 08/2003
3	LigandsIBA 12/2012 - 06/2010
2	Vitamin D FDA LinkGeneric 01/2022 - 04/2011
2	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 01/2021
2	Interleukin-15 (Interleukin 15)IBA 01/2021 - 01/2017
2	Mechanistic Target of Rapamycin Complex 1IBA 01/2020 - 01/2016
2	malic acid (malate)IBA 02/2019 - 12/2012
2	Antiviral Agents (Antivirals)IBA 01/2019 - 03/2012
2	Caspase 3 (Caspase-3)IBA 10/2018 - 12/2015
2	Concanavalin AIBA 01/2017 - 01/2017
2	Small Interfering RNA (siRNA)IBA 01/2017 - 01/2010
2	Polysaccharides (Glycans)IBA 12/2015 - 07/2013
2	AcetylglucosamineIBA 12/2015 - 07/2013
2	Carrier Proteins (Binding Protein)IBA 12/2015 - 10/2011
2	Dextran SulfateIBA 07/2015 - 12/2012
2	Neutralizing AntibodiesIBA 02/2015 - 01/2013
2	Interleukin-6 (Interleukin 6)IBA 11/2014 - 08/2014
2	bavachininIBA 04/2014 - 11/2013
2	Fatty Acid-Binding ProteinsIBA 09/2013 - 06/2012
2	AutoantibodiesIBA 07/2013 - 06/2013
2	Interleukin-12 (IL 12)IBA 07/2013 - 08/2007
2	CalciumIBA 05/2013 - 04/2011
2	AntibodiesIBA 12/2012 - 09/2004
2	CholesterolIBA 12/2012 - 02/2010
2	NK-007IBA 12/2012 - 09/2012
2	Collagen Type II (Type II Collagen)IBA 01/2011 - 03/2006
2	Interferon-gamma (Interferon, gamma)IBA 01/2008 - 08/2003
1	EpitopesIBA 03/2022
1	HLA-A2 Antigen (HLA A2 Antigen)IBA 03/2022
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2022
1	HydrogenIBA 01/2022
1	Complement System Proteins (Complement)IBA 01/2022

Therapy/Procedure

15	Immunotherapy 10/2022 - 11/2010
9	Therapeutics 01/2022 - 07/2010
3	Drug Therapy (Chemotherapy) 01/2022 - 08/2012
2	Radiotherapy 01/2022 - 01/2019
1	Respiratory Therapy (Therapy, Respiratory) 01/2022
1	Otoscopes 01/2022